Peptide Encyclopedia / ACE-031
EncyclopediaACE-031 is a soluble decoy receptor fusion protein that traps myostatin and related signals to take the brakes off muscle growth. Development reached only early-phase human trials before Acceleron and Shire halted it over safety signals, so it sits abandoned and approved nowhere. Educational, not medical advice.
| Category | Growth Hormone |
| Regulatory status | Investigational only and discontinued. |
A soluble decoy receptor fusion protein (activin receptor type IIB ectodomain fused to IgG1 Fc) that sequesters myostatin and related TGF-beta family ligands, removing their inhibition of muscle growth to increase muscle mass.
uncertain; engineered as a long-acting fusion protein dosed infrequently, but no robust public human PK. Commonly reported use/dosing: No legitimate clinical protocol; development was halted. Any current circulation is via unregulated research-chemical channels and is not a validated regimen.
Investigational only and discontinued. Acceleron/Shire ended development (notably a Duchenne muscular dystrophy program) after safety signals. Not approved anywhere; not legally available as a therapeutic.
Trials were stopped due to safety concerns including epistaxis (nosebleeds), gingival/mucosal bleeding, and telangiectasias (dilated blood vessels), reflecting off-target vascular effects of ActRIIB blockade. Discontinued investigational agent; use is strongly discouraged.
Early-phase human trials only, terminated; abandoned investigational compound.
PepWise is an informational and educational tracking tool, not medical advice and not a medical device. ACE-031 may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.
