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Peptide Encyclopedia / BAM15

Encyclopedia

BAM15

BAM15 is a small-molecule mitochondrial uncoupler rather than a peptide, studied for burning energy and fat by leaking the mitochondrial proton gradient. In mice it cut fat mass and improved insulin sensitivity, but no human trials exist and it stays a research chemical. Educational, not medical advice.

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CategoryGLP-1 / Metabolic
Regulatory statusNot FDA-approved.

Mechanism

A small-molecule mitochondrial protonophore/uncoupler -- NOT a peptide. It dissipates the mitochondrial proton gradient to increase energy expenditure and fat oxidation; in mice it reduces fat mass and improves insulin sensitivity without reducing food intake or raising body temperature.

Half-life

Not well established in humans; preclinical data only. It is a small molecule, not a peptide.

Regulatory status

Not FDA-approved. No completed human clinical trials. Sold as a research chemical / for laboratory use only.

Safety

Mitochondrial uncouplers as a class carry serious safety concerns (the historic uncoupler DNP caused fatal hyperthermia); although BAM15 showed a wider safety margin than older uncouplers in animals, human safety is entirely unestablished.

Evidence

Preclinical only -- cell and rodent studies; no human trials.

Sources

PepWise is an informational and educational tracking tool, not medical advice and not a medical device. BAM15 may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.