Peptide Encyclopedia / Cortagen
EncyclopediaCortagen is a short synthetic peptide from the Khavinson bioregulator family, sold as a brain-cortex agent though its mechanism stays unproven. Evidence rests on Russian preclinical and small clinical reports, and it trades as a research chemical, not an FDA-approved drug. Educational only, not medical advice.
| Category | Cognitive |
| Regulatory status | Not FDA-approved; research chemical / gray-market in the US. |
A short synthetic peptide (commonly cited as a tetrapeptide, e.g., Ala-Glu-Asp-Pro) from the Khavinson 'bioregulator' family, marketed as a brain-cortex-targeted agent. The proposed mechanism (largely unproven) is tissue-specific modulation of gene expression / protein synthesis in cortical cells. Mechanism should be regarded as proposed rather than established.
uncertain / limited human pharmacokinetic data; short peptides are expected to be rapidly cleared, but no rigorous human PK exists.
Not FDA-approved; research chemical / gray-market in the US. Some Khavinson peptides are sold as supplements/registered preparations within Russia, but Cortagen is not an FDA-approved drug and is sold as a research chemical in the West.
Human safety data are minimal and come almost entirely from Russian sources. Short peptides are often presumed low-risk due to rapid clearance, but this is not a substitute for controlled safety data. Gray-market purity/identity unverified.
mostly Russian (Khavinson group and affiliates) preclinical and small clinical reports, with little to no independent Western peer-reviewed replication.
PepWise is an informational and educational tracking tool, not medical advice and not a medical device. Cortagen may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.
