Encyclopedia

GHRP-2

GHRP-2 is a growth hormone-releasing peptide and ghrelin-receptor agonist that prompts the pituitary to release GH while raising appetite. Human data stay limited to early-phase and animal studies, it holds no FDA approval, and it remains restricted under FDA Category 2. Educational only, not medical advice.

Track GHRP-2 →Dose tools

Category	Growth Hormone
Half-life	15-60 minutes
Regulatory status	Not FDA-approved.

Mechanism

A growth hormone-releasing peptide / ghrelin-receptor agonist that stimulates pituitary GH release; also raises appetite and can modestly increase cortisol/prolactin.

Half-life

~15-60 minutes; short and somewhat uncertain.

Regulatory status

Not FDA-approved. On FDA Category 2; as of 2026 reporting, expected to REMAIN restricted (not moving toward

Safety

Increased appetite, water retention, possible cortisol/prolactin elevation, injection-site reactions. Long-term safety not established.

Evidence

Limited human data; mostly early-phase/animal studies and anecdotal use.

Track GHRP-2 in PepWise

Log every dose and injection site, get the reconstitution and units math automatically, follow your cycle, and record how you feel, then export a provider report. GHRP-2 tracker, free to start.

Sources

Laferrere B, et al. GHRP-2, like ghrelin, increases food intake in healthy men. J Clin Endocrinol Metab. 2005;90(2):611-614. https://pubmed.ncbi.nlm.nih.gov/15699539/
Mericq V, et al. Effects of 8 months treatment with graded doses of a GH-releasing peptide in GH-deficient children. J Clin Endocrinol Metab. 1998;83(7):2355-2360. https://pubmed.ncbi.nlm.nih.gov/9661608/
Arvat E, et al. Effects of GHRP-2 and hexarelin on GH, prolactin, ACTH and cortisol in man. Peptides. 1997;18(6):885-891. https://pubmed.ncbi.nlm.nih.gov/9285939/
Doi N, et al. Pharmacological characteristics of KP-102 (GHRP-2). Arzneimittelforschung. 2004;54(12):857-867. https://pubmed.ncbi.nlm.nih.gov/15646370/
Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. https://pubmed.ncbi.nlm.nih.gov/9849822/

PepWise is an informational and educational tracking tool, not medical advice and not a medical device. GHRP-2 may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.