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Peptide Encyclopedia / GHRP-6

Encyclopedia

GHRP-6

GHRP-6 is a growth hormone-releasing peptide and ghrelin-receptor agonist that triggers pituitary GH release and a strong rise in hunger. Human data stay limited to early-phase and animal studies, it holds no FDA approval, and it stays restricted under FDA Category 2. Educational only, not medical advice.

Track GHRP-6 →Dose tools
CategoryGrowth Hormone
Half-life15-60 minutes
Regulatory statusNot FDA-approved.

Mechanism

A growth hormone-releasing peptide / ghrelin-receptor agonist that stimulates pituitary GH release and strongly increases hunger.

Half-life

~15-60 minutes; short and uncertain.

Regulatory status

Not FDA-approved. On FDA Category 2; as of 2026 reporting, expected to REMAIN restricted. Prohibited by WADA.

Safety

Pronounced increased appetite, water retention, possible cortisol/prolactin rise, injection-site reactions. Long-term safety not established.

Evidence

Limited human data; mostly early-phase/animal studies and anecdotal use.

Track GHRP-6 in PepWise

Log every dose and injection site, get the reconstitution and units math automatically, follow your cycle, and record how you feel, then export a provider report. GHRP-6 tracker, free to start.

Sources

  1. Lei T, et al. GHRP-6 stimulates phosphatidylinositol turnover in human pituitary somatotroph cells. J Mol Endocrinol. 1995;14(1):135-138. https://pubmed.ncbi.nlm.nih.gov/7772238/
  2. Berlanga J, et al. GHRP-6 prevents oxidant cytotoxicity and reduces myocardial necrosis in acute MI. Clin Sci (Lond). 2007;112(4):241-250. https://pubmed.ncbi.nlm.nih.gov/16989643/
  3. Mendoza Mari Y, et al. GHRP-6 enhances the healing process and esthetic outcome of wounds. Plast Surg Int. 2016;2016:7340426. https://pubmed.ncbi.nlm.nih.gov/27200188/
  4. Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci. 1998;54(12):1316-1329. https://pubmed.ncbi.nlm.nih.gov/9893708/
  5. Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-561. https://pubmed.ncbi.nlm.nih.gov/9849822/

PepWise is an informational and educational tracking tool, not medical advice and not a medical device. GHRP-6 may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.