PepWisePepWise
Start free

Peptide Encyclopedia / Noopept

Encyclopedia

Noopept

Noopept is a synthetic dipeptide nootropic reported to support neuroprotection and cognition through NGF, BDNF, and glutamate signaling. The FDA has not approved it and it does not qualify as a lawful US supplement ingredient, though Russia markets it as a pharmaceutical. Educational only, not medical advice.

Start free →Dose tools
CategoryCognitive
Half-life30-60 minutes for the parent compou
Regulatory statusNot FDA-approved and not a lawful dietary-supplement ingredient in the US.

Mechanism

A synthetic dipeptide nootropic (N-phenylacetyl-L-prolylglycine ethyl ester) reported to have neuroprotective and cognitive effects, possibly via NGF/BDNF and glutamate signaling.

Half-life

~30-60 minutes for the parent compound; short, with effects reported to outlast plasma levels.

Regulatory status

Not FDA-approved and not a lawful dietary-supplement ingredient in the US. An approved pharmaceutical in Russia/CIS. In the US it is sold as a research chemical / gray-market nootropic.

Safety

Generally well tolerated in Russian and community use (possible headache, irritability, fatigue). US oversight limited; long-term safety not well established outside approved markets.

Evidence

Human clinical data primarily from Russia/CIS; limited Western data plus anecdotal use.

Sources

PepWise is an informational and educational tracking tool, not medical advice and not a medical device. Noopept may be experimental, restricted, or prescription-only; many research peptides are not FDA-approved. Consult a licensed healthcare provider before starting, changing, or stopping any protocol. Operated by STC Consulting, Inc.